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Top 5 Best Drain Cleaners for Toilets

Best Drain Cleaner for Toilets
If you have a clogged toilet and no amount of plunging or toilet snaking is doing the trick, you might have to resort to some other methods. Most people, when a toilet is severely clogged, will resort to a drain cleaner for toilets, some kind of chemical or enzymatic compound that can eat through clogs.
With that being said, there are so many different options out there, that choosing the right one can be hard, not to mention that many drain cleaners are not suitable for toilets. Today we are here to help you find the best drain cleaner for toilets. We’ve got a comprehensive buying guide, plus we’ve reviewed some of the best possible products on the market too.

Our Overall #1 Rated Pick

Our top pick for the number one best drain cleaner for toilets has to be DISSOLVE Liquid Hair & Grease Clog Remover. Now, let’s keep in mind that it is a chemical option, as opposed to enzymatic, it is fairly safe to use. In all reality, for serious clogs, this might just be the best option.

  • DISSOLVE Liquid Hair & Grease Clog Remover is designed to be safer than most other chemical toilet drain cleaners. Although it is not 100% eco-friendly and safe, it is less harmful than most other options out there.
  • DISSOLVE Liquid Hair & Grease Clog Remover is designed with a very thick consistency, which helps it stay in place, stick to drains, and eat through clogs before being flushed down. In other words, it won’t just run straight down the drain.
  • This particular drain cleaner is safe to use for all types of plumbing, whether for toilets, RVs, septic systems, sinks, bathtubs, or anything in between.
  • DISSOLVE Liquid Hair & Grease Clog Remover is proven to be extremely fast acting and will begin working in a matter of minutes after application.
  • This particular drain cleaner is very easy to use. Simply pour it into the toilet and let it do its job.

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Drain Cleaner for Toilet – Buying Guide & FAQ

Purchasing Factors To Consider For Toilet Drain Cleaner

Before you go out and buy any drain cleaner for toilets, there are a few important considerations you need to keep in mind, so let’s go over these right now.

Specific Use

Before anything else, the absolute most important thing to look for is that the product you get is safe to use for toilets. You might think that a drain is a drain, but this is not so.
We aren’t going to get into the science of it, but many drain cleaners designed for tubs and sinks are not suitable for toilets, and in the worst case scenario, if used for toilets, these products can cause pipes to burst. So, make sure that the drain cleaner in question is indeed toilet safe.

Chemicals vs Enzymes

The next consideration to make when purchasing liquid pipe cleaner is whether you want to go for something made with heavy chemicals or with enzymes.
Realistically, the chemical options are going to do a much better job, but they aren’t eco friendly. Enzymatic clog removers for toilets do work but they may take longer to take effect and may not be quite as effective overall.


When purchasing toilet unclogging liquid, seeing as our planet is on the brink of destruction due to pollution, buying something non-toxic and eco-friendly is recommended.
Of course, chemical cleaners are not eco friendly, much less so than enzymatic cleaners. However, if you go for the right product, a select few chemical based options may be partially eco-friendly.


The next thing to keep an eye on when selecting the right drain openers for toilets is how thick or viscous the liquid in question is.
What you definitely don’t want is a very thin liquid. Thin liquids will usually run right past clogs and are not very effective. You need to get a drain cleaner that is very thick and viscous, so it can actually stick around until the job is done.

Unclogging Potential

Of course, the whole point of any liquid plumber for toilets is to eat through clogs. Therefore, when looking at products, make sure to get one that has the ability to eat through grease, hair, human waste and toilet paper alike.

Working Time

Although taking a bit longer to unclog a toilet may not be a huge deal, it always helps to have a drain cleaner that is fast acting. The chemical heavy options tend to work much faster than enzymatic options, but of course are not nearly as safe.

Quantity & Required Dosage

The other thing you want to consider before making a purchase is how much liquid comes in each bottle, as well as how much is needed for a single treatment. Some products can be used dozens of times, some only go as far as one or two treatments.

Can I use sink drain cleaner on toilets?

Unless otherwise stated, no, sink and tub drain cleaners cannot be used for toilets.

Will drain cleaner eat through inorganic compounds?

No, drain cleaners are designed to eat through organic compounds, but will not eat through other obstacles.

Can I use Drano to unclog toilets?

No, Drano is not toilet safe and it will generate a lot of heat in the pipes, and may actually cause your toilet to more or less explode.

When should I use toilet drain cleaner?

If you have a seriously clogged toilet and you have already tried using the toilet plunger, and you have also used a toilet snake, your only option may be a drain cleaner. A drain cleaner is a good way to go if you don’t want to pay hundreds of dollars for a plumber.

Are there other ways to unclog toilets

There are some other methods of unclogging toilets which may work, which can include pouring boiling water down the drain, as well as pouring baking soda and vinegar into the toilet and then attempting to flush.

The Best Drain Cleaner for Toilet

DISSOLVE Liquid Hair & Grease Clog Remover

DISSOLVE Liquid Hair & Grease Clog Remover

DISSOLVE Liquid Hair & Grease Clog Remover is designed to eat through hair, grease, soap, toilet paper, and human waste alike.
Everything organic will be dissolved and then easily flushed down the toilet. This product features a really thick and viscous composition, so it stays where it’s supposed to be, instead of just running down the pipes without getting the chance to dissolve the clogs.
DISSOLVE Liquid Hair & Grease Clog Remover is designed to work within minutes. Moreover, this product is safe for toilets, sinks, bathtubs, and everything in between. This is a very easy to use product. Simply pour it into the toilet, wait for a few minutes, and then flush.
The bottle is neatly divided into two portions so you know exactly how much to use. Although not 100% eco-friendly, it is a much safer and more environmentally friendly option than most others.
Use for any drain
Eats through all organics
Fast acting
Fairly eco-friendly
Easy to use
Smells bad
Only 2 applications

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Professor Amos’ SuperFast Drain Cleaner

Professor Amos' SuperFast Drain Cleaner

For serious drain clogs, ones you haven’t been able to resolve using any other methods, this Professor Amos’ SuperFast Drain Cleaner might be your best bet. Here you get two bottles of this drain cleaner, and depending on the severity of the clog, each bottle can last for up to six applications.
This product is safe for all types of plumbing including toilets, sinks, bathtubs, and more.
Keep in mind that Professor Amos’ SuperFast Drain Cleaner is commercial strength and loaded with chemicals. It is perhaps the most effective option for quickly eating through any type of clog, whether human waste, toilet paper, grease, or hair.
However, this is a very chemical heavy toilet drain cleaner, so it’s absolutely not eco-friendly in the least.
Extremely effective for all organic compounds
Many applications with one purchase
Safe for all types of pluming
Fast acting
Not eco-friendly in the least

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Liquid Lightning Buffered Sulfuric Acid Drain Cleaner

Liquid Lightning Buffered Sulfuric Acid Drain Cleaner
For serious clogs, this sulfuric acid based drain cleaner is a very effective option. Now, sulfuric acid is not very safe, it’s not eco-friendly, and it will burn skin too.
However, sulfuric acid is also one of the best chemicals out there which can quickly and effectively eat through all organic materials like grease, human waste, toilet paper, hair, and more.
Liquid Lightning Buffered Sulfuric Acid Drain Cleaner is a very fast acting option that can unclog drains within minutes. This product is also very simple to use. Just pour it in the drain and let it work its magic. This particular product can be used for all types of plumbing including toilets.
Safe for all types of plumbing
Eats through all organic compounds
Very fast acting
Easy to use
Not eco-friendly

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InVade Bio Drain

InVade Bio Drain
If you do not want to pour harsh chemicals down the toilet due to environmental concerns, this InVade Bio Drain makes for a much safe and eco-friendly option.
This product is designed with probiotic enzymes, or in other words, special bacteria which can eat through organic compounds. It has the ability to quickly eat through human waste, hair, grease, toilet paper, and more.
InVade Bio Drain comes in a 1 gallon bottle, and about 4 ounces is more than enough for stubborn clogs, so it should last for quite some time.
This product is also designed to be extremely thick and viscous, so it actually attaches itself to clogs to eat through them, instead of just running down the tubes. This product can be used for all sorts of drains, not just toilets.
Works for all types of clogs
Effective for all plumbing types
Very thick and viscous
Much safer than most other options
Not quite as effective as chemical heavy products

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MegaMicrobes Drain Cleaner

MegaMicrobes Drain Cleaner
MegaMicrobes Drain Cleaner is designed as a much safer alternative to chemical heavy drain cleaners and is listed in the EPA’s safer choice program. This is an enzyme based drain cleaner, so instead of chemicals it uses bacteria to eat through clogs.
This product is ideal for breaking down fats, carbohydrates, proteins, and hydrocarbons, or in other words, mostly anything that could be clogging your toilet.
Moreover, this MegaMicrobes Drain Cleaner can be used for toilets and all other types of drains alike. Moreover, this is an eco-friendly, non-toxic, and perfectly safe product to pour down drains. Finally, you can get up to 32 uses per bottle, although realistically this tops out at about 20 uses per bottle.
Eco-friendly and non-toxic
Eats through most clogs
Safe for all drains
Easy to use
Many applications out of a single bottle
Splatters and makes a mess

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Our Pick

DISSOLVE Liquid Hair & Grease Clog Remover

DISSOLVE Liquid Hair & Grease Clog Remover
To reiterate, the top pick for the best drain cleaner for toilets is DISSOLVE Liquid Hair & Grease Clog Remover. As far as the chemical heavy options go, it’s one of the much safer and less toxic products.
Moreover, DISSOLVE Liquid Hair & Grease Clog Remover is designed to work with all types of plumbing including toilets, and it can eat through all types of organic materials. It also happens to be very fast acting. It may not smell nice and you may not get too many applications out of a single bottle, but it does work extremely well.

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Whether you go for an enzymatic or a straight chemical based drain cleaner, the most important thing to keep in mind is that whatever product you get, it needs to be toilet safe. There are plenty of drain cleaners out there which are not suited for toilets and can literally cause pipes to explode, so beware! Furthermore, also make sure to get something that has a thick consistency, as this is a large factor which determines just how well the product in question works.

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